BDBM50316614 (1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate::CHEMBL1095183

SMILES COC(=O)N1C[C@@H]2[C@@H](CC[C@H]1CN2C(=O)Cc1ccc(Cl)c(Cl)c1)N1CCCC1

InChI Key InChIKey=OMVSGZSRXSCVQR-KFKAGJAMSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316614   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316614((1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi:  515nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316614((1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316614((1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316614((1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316614((1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed