BDBM50316692 CHEMBL1094212::N-[2-(7-{4-(4'-Hydroxymethylbiphenyl-4-yloxy}butoxy)-naphthalen-1-yl)ethyl]acetamide

SMILES CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(cc3)-c3ccc(CO)cc3)cc12

InChI Key InChIKey=VDBKGGONHKGNTE-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316692   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316692(CHEMBL1094212 | N-[2-(7-{4-(4'-Hydroxymethylbiphen...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316692(CHEMBL1094212 | N-[2-(7-{4-(4'-Hydroxymethylbiphen...)
Affinity DataKi:  6.5nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316692(CHEMBL1094212 | N-[2-(7-{4-(4'-Hydroxymethylbiphen...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316692(CHEMBL1094212 | N-[2-(7-{4-(4'-Hydroxymethylbiphen...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed