BDBM50316693 CHEMBL1095831::N-[2-(7-{4-[8-(2-Acetylaminoethyl)-5,6,7,8-tetrahydronaphthalen-2-yloxy]butoxy}naphthalen-1-yl)ethyl]acetamide

SMILES CC(=O)NCCC1CCCc2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12

InChI Key InChIKey=DNGCHGMDDOPAPX-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316693   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316693(CHEMBL1095831 | N-[2-(7-{4-[8-(2-Acetylaminoethyl)...)
Affinity DataKi:  0.260nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316693(CHEMBL1095831 | N-[2-(7-{4-[8-(2-Acetylaminoethyl)...)
Affinity DataKi:  6.80nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316693(CHEMBL1095831 | N-[2-(7-{4-[8-(2-Acetylaminoethyl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316693(CHEMBL1095831 | N-[2-(7-{4-[8-(2-Acetylaminoethyl)...)
Affinity DataEC50:  7.80nMAssay Description:Agonist activity at human human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed