BDBM50317161 (2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime::CHEMBL1088704
SMILES Oc1ccc2[nH]c(c(N=[OH+])c2c1)-[c-]1c2cc(ccc2[nH]c1=O)[N+]([O-])=O
InChI Key InChIKey=AHIMCOQTGQUIII-UHFFFAOYSA-O
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50317161
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK1/cyclin B after 40 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant TrKa preincubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant IKK-beta preincubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant auroraA preincubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair