BDBM50317207 CHEMBL1088517::N-cyclohexyl-2-(7,8-dihydro-4H-isoxazolo[3,4-d]azepin-6(5H)-yl)-N-ethylacetamide

SMILES CCN(C1CCCCC1)C(=O)CN1CCc2conc2CC1

InChI Key InChIKey=DKFPJVQUCNQTLS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317207   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317207(CHEMBL1088517 | N-cyclohexyl-2-(7,8-dihydro-4H-iso...)
Affinity DataKi:  15nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317207(CHEMBL1088517 | N-cyclohexyl-2-(7,8-dihydro-4H-iso...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed