BDBM50317384 CHEMBL1096042::ethyl 5-(4-nitrophenyl)-4,6-dioxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate

SMILES CCOC(=O)c1n[nH]c2C(=O)N(C(=O)c12)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=KJAJWCHANQMLIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317384   

TargetExportin-1(Homo sapiens (Human))
Georg-August-University G£Ttingen

Curated by ChEMBL
LigandPNGBDBM50317384(CHEMBL1096042 | ethyl 5-(4-nitrophenyl)-4,6-dioxo-...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of fluorescently labeled PKI phi(0)Leu NES binding to human CRM1 expressed in Escherichia coli BL21 (DE3) by fluorescence polarization com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50317384(CHEMBL1096042 | ethyl 5-(4-nitrophenyl)-4,6-dioxo-...)
Affinity DataIC50:  3.19E+4nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed