BDBM50317650 6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-1,4,7,10-tetraoxotetradecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-6-yl)-N-hydroxyhexanamide::CHEMBL1096986

SMILES ONC(=O)CCCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

InChI Key InChIKey=DAMGSDKDFKQTGM-GCXHJFECSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50317650   

TargetHistone deacetylase 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50317650(6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of HDAC5 catalytic domain expressed in Escherichia coli after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50317650(6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of full length HDAC1 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50317650(6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of human full length HDAC8 expressed in Escherichia coli after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50317650(6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...)
Affinity DataIC50:  2.47E+4nMAssay Description:Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50317650(6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of human HDAC4 catalytic domain expressed in Escherichia coli BL21 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed