BDBM50317763 3-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)pyrazine-2-carboxamide::CHEMBL1098517

SMILES Fc1ccc(NC(=O)c2nccnc2Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(F)c1

InChI Key InChIKey=MHWOEFYKEQWZSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50317763   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50317763(3-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...)
Affinity DataIC50:  55nMAssay Description:Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed