BDBM50317923 (2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)methyl)tetrahydro-4-phenyl-2H-pyran-4-ol::CHEMBL1095082

SMILES CCSC[C@@H]1C[C@](O)(C[C@@H](O1)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=FPGNAQGJVPLCGL-ZCNNSNEGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317923   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50317923((2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)met...)
Affinity DataIC50:  413nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50317923((2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)met...)
Affinity DataIC50:  1.82nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed