BDBM50317945 CHEMBL1095450::N-hydroxy-3-(3-(5-methyl-1-(2-morpholinoethyl)-4-phenyl-1H-imidazol-2-yl)phenyl)acrylamide

SMILES Cc1c(nc(-c2cccc(\C=C\C(=O)NO)c2)n1CCN1CCOCC1)-c1ccccc1

InChI Key InChIKey=ARMZVBSGMUBKGW-ZHACJKMWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317945   

TargetHistone deacetylase 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317945(CHEMBL1095450 | N-hydroxy-3-(3-(5-methyl-1-(2-morp...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317945(CHEMBL1095450 | N-hydroxy-3-(3-(5-methyl-1-(2-morp...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317945(CHEMBL1095450 | N-hydroxy-3-(3-(5-methyl-1-(2-morp...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed