BDBM50317946 CHEMBL1095451::N-hydroxy-3-(3-(5-methyl-1-phenethyl-4-phenyl-1H-imidazol-2-yl)phenyl)acrylamide

SMILES Cc1c(nc(-c2cccc(\C=C\C(=O)NO)c2)n1CCc1ccccc1)-c1ccccc1

InChI Key InChIKey=ZKDXRRPJVSHVTP-FOCLMDBBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317946   

TargetHistone deacetylase 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317946(CHEMBL1095451 | N-hydroxy-3-(3-(5-methyl-1-pheneth...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317946(CHEMBL1095451 | N-hydroxy-3-(3-(5-methyl-1-pheneth...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317946(CHEMBL1095451 | N-hydroxy-3-(3-(5-methyl-1-pheneth...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed