BDBM50317951 CHEMBL1096433::N-hydroxy-3-(3-(4-methyl-1-phenethyl-5-phenyl-1H-imidazol-2-yl)phenyl)acrylamide

SMILES Cc1nc(-c2cccc(\C=C\C(=O)NO)c2)n(CCc2ccccc2)c1-c1ccccc1

InChI Key InChIKey=LGYPNWMTVBKIJM-FOCLMDBBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317951   

TargetHistone deacetylase 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317951(CHEMBL1096433 | N-hydroxy-3-(3-(4-methyl-1-pheneth...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317951(CHEMBL1096433 | N-hydroxy-3-(3-(4-methyl-1-pheneth...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317951(CHEMBL1096433 | N-hydroxy-3-(3-(4-methyl-1-pheneth...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed