BDBM50318137 (R)-3-ethyl-5-(3-methylpiperazin-1-yl)-N-(pyrimidin-4-yl)-1-(2-(2,2,2-trifluoroethoxy)ethyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine::CHEMBL1095121

SMILES CCc1nn(CCOCC(F)(F)F)c2c(Nc3ccncn3)nc(nc12)N1CCN[C@H](C)C1

InChI Key InChIKey=UCRSYBKADUKGLT-CYBMUJFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318137   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318137((R)-3-ethyl-5-(3-methylpiperazin-1-yl)-N-(pyrimidi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG expressed by patch clam electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318137((R)-3-ethyl-5-(3-methylpiperazin-1-yl)-N-(pyrimidi...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed