BDBM50318154 8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one::CHEMBL1094487

SMILES CCc1ccc(CC)c2CC(Cc12)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=SARQODHPNUVLSS-QFIPXVFZSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318154   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318154(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
Affinity DataKi:  692nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318154(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
Affinity DataIC50:  75nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318154(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
Affinity DataEC50:  115nMAssay Description:Agonist activity at human beta2 adrenergic receptor assessed as increase in cAMP level by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed