BDBM50318184 CHEMBL1095466::N-(3-bromophenyl)-6-(2-methylbenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES Cc1ccccc1Cc1cc2c(Nc3cccc(Br)c3)ncnc2[nH]1

InChI Key InChIKey=YBAKNSGHVALZHX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318184   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318184(CHEMBL1095466 | N-(3-bromophenyl)-6-(2-methylbenzy...)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of VEGFR2 phosphorylation in human U251 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318184(CHEMBL1095466 | N-(3-bromophenyl)-6-(2-methylbenzy...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human SF539 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318184(CHEMBL1095466 | N-(3-bromophenyl)-6-(2-methylbenzy...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of VEGFR1 phosphorylation in human A498 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318184(CHEMBL1095466 | N-(3-bromophenyl)-6-(2-methylbenzy...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of EGFR phosphorylation in human A431 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed