BDBM50318188 6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL1098440

SMILES Clc1ccc(Cc2cc3c(Nc4cccc(c4)C#C)ncnc3[nH]2)c(Cl)c1

InChI Key InChIKey=FQFXJYXFHKOMBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318188   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of VEGFR2 phosphorylation in human U251 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50:  1.42E+5nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human SF539 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of VEGFR1 phosphorylation in human A498 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318188(6-(2,4-dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrr...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of EGFR phosphorylation in human A431 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed