BDBM50318238 4-((5S,9R)-3-(3,5-Dichlorophenyl)-1-methyl-2,4-dioxo-7-(pyridin-2-yl)-1,3,7-triazaspiro[4.4]nonan-9-yl)benzonitrile::CHEMBL1097384
SMILES CN1C(=O)N(C(=O)[C@]11CN(C[C@H]1c1ccc(cc1)C#N)c1ccccn1)c1cc(Cl)cc(Cl)c1
InChI Key InChIKey=OERBTZBYLXYWQC-SQJMNOBHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50318238
TargetIntegrin alpha-L(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of LFA1-mediated IL2 mRNA level in SEB-stimulated human whole blood measured after 6 hrs post stimulation by RT-PCR analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-L(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair