BDBM50318639 6-hydroxy-1-methoxy-9H-xanthen-9-one::CHEMBL1084265

SMILES COc1cccc2oc3cc(O)ccc3c(=O)c12

InChI Key InChIKey=UKPKWIBNYWUEMK-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50318639   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50318639(6-hydroxy-1-methoxy-9H-xanthen-9-one | CHEMBL10842...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of KDM5A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50318639(6-hydroxy-1-methoxy-9H-xanthen-9-one | CHEMBL10842...)
Affinity DataEC50:  415nMAssay Description:Agonist activity at ERalpha expressed in yeast assessed as alpha-galactosidase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50318639(6-hydroxy-1-methoxy-9H-xanthen-9-one | CHEMBL10842...)
Affinity DataEC50:  822nMAssay Description:Agonist activity at ERbeta expressed in CHO-K1 cells by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50318639(6-hydroxy-1-methoxy-9H-xanthen-9-one | CHEMBL10842...)
Affinity DataEC50:  4.16E+3nMAssay Description:Agonist activity at ERalpha expressed in CHO-K1 cells by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50318639(6-hydroxy-1-methoxy-9H-xanthen-9-one | CHEMBL10842...)
Affinity DataEC50:  49.8nMAssay Description:Agonist activity at ERbeta expressed in yeast assessed as alpha-galactosidase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed