BDBM50318652 (E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3-chlorophenyl)-4-oxobutanamide::4-[2-(anthracen-9-ylmethylidene)hydrazino]-N-(3-chlorophenyl)-4-oxobutanamide::CHEMBL1084866::NadD inhibitor 1_02::US8785499, 1_02

SMILES Clc1cccc(NC(=O)CCC(=O)N\N=C\c2c3ccccc3cc3ccccc23)c1

InChI Key InChIKey=OJLFRDWWYAPUAJ-JVWAILMASA-N

Data  6 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318652   

TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50318652((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite gre...More data for this Ligand-Target Pair
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50318652((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of ATP substrate by malachite gree...More data for this Ligand-Target Pair
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50318652((E)-4-(2-(anthracen-9-ylmethylene)hydrazinyl)-N-(3...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of substrate by malachite green re...More data for this Ligand-Target Pair