BDBM50319069 (2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)pyridazin-3-yl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1084259::US8541380, 68

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(nn2)-c2ccc3OCCOc3c2)c1

InChI Key InChIKey=SOYYFQTUYHOTJP-RXFVIIJJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319069   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50319069((2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(2,3-dihydroben...)
Affinity DataIC50:  103nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50319069((2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(2,3-dihydroben...)
Affinity DataIC50:  103nMAssay Description:Inhibition assay using hSGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent