BDBM50319818 (+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl)piperazine::(-)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl)piperazine::1-(2-(2-(DIFLUOROMETHOXY)PHENYL)-1-PHENYLETHYL)PIPERAZINE (ENANTIOMERIC MIX)::1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl)piperazine::CHEMBL1083708

SMILES FC(F)Oc1ccccc1CC(N1CCNCC1)c1ccccc1

InChI Key InChIKey=VCVDPONUNCPTCQ-UHFFFAOYSA-N

Data  9 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50319818   

LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataIC50: 1.07E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataIC50: 1.07E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataIC50: 1.27E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  6.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  6.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818(CHEMBL1083708 | 1-(2-(2-(difluoromethoxy)phenyl)-1...)
Affinity DataKi:  6.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed