BDBM50319831 (R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol::CHEMBL1084971

SMILES Oc1ccccc1C[C@@H](N1CCNCC1)c1ccccc1

InChI Key InChIKey=SBKGLFTUHHUCII-QGZVFWFLSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50319831   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319831((R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | C...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319831((R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | C...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319831((R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | C...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319831((R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | C...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319831((R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | C...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed