BDBM50320254 1-(1-cyclopropylethyl)-5-(6-ethoxy-2-(trifluoromethyl)pyridin-3-ylamino)-3-methyl-1,2,4-triazin-6(1H)-one::CHEMBL1083592

SMILES CCOc1ccc(Nc2nc(C)nn(C(C)C3CC3)c2=O)c(n1)C(F)(F)F

InChI Key InChIKey=VAHUPXXWRCYHIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320254   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50320254(1-(1-cyclopropylethyl)-5-(6-ethoxy-2-(trifluoromet...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]Tyr-ovine CRF from rat CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed