BDBM50320350 CHEMBL1082387::phenyl(4-(4-o-tolylphthalazin-1-yl)piperazin-1-yl)methanone

SMILES Cc1ccccc1-c1nnc(N2CCN(CC2)C(=O)c2ccccc2)c2ccccc12

InChI Key InChIKey=WZEDNZDFRJGPBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320350   

TargetSmoothened homolog(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50320350(CHEMBL1082387 | phenyl(4-(4-o-tolylphthalazin-1-yl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human SMO expressed in HEPM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed