BDBM50320715 8-Fluoro-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl)phenoxy]propyl}-5-(4-methanesulfonylbenzyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride::CHEMBL1164943

SMILES COC1(CCOCC1)c1cc(F)cc(OCCCN2CCc3c(C2)c2cc(F)ccc2n3Cc2ccc(cc2)S(C)(=O)=O)c1

InChI Key InChIKey=DMAVCPVMLQXHRY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50320715   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320715(8-Fluoro-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-...)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320715(8-Fluoro-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320715(8-Fluoro-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-...)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed