BDBM50321310 CHEMBL4175786::US10688093, Compound 229_0226_0284::US11701353, Compound 229_0226_0284

SMILES CCCNc1ccc2ncc(-c3cccc(O)c3)n2n1

InChI Key InChIKey=BBRVCZSXNXYZKS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321310   

TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
TBA

Curated by ChEMBL
LigandPNGBDBM50321310(CHEMBL4175786 | US10688093, Compound 229_0226_0284...)
Affinity DataKi:  37nMAssay Description:Inhibition of Plasmodium falciparum recombinant CDPK1 expressed in Escherichia coli expression system after 1 hr in presence of [gamma33P]ATP by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50321310(CHEMBL4175786 | US10688093, Compound 229_0226_0284...)
Affinity DataIC50:  592nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50321310(CHEMBL4175786 | US10688093, Compound 229_0226_0284...)
Affinity DataIC50:  930nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent