BDBM50321447 2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benzenesulfonamide::CHEMBL1171969

SMILES FC(F)(F)c1cccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c1

InChI Key InChIKey=SIFZUZIJSUIQHX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321447   

TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321447(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CDK7/Cyclin H/MAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321447(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)
Affinity DataIC50:  5.88E+4nMAssay Description:Inhibition of human CDK6/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321447(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)
Affinity DataIC50:  600nMAssay Description:Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321447(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321447(2,4,5-trichloro-N-(3-(trifluoromethyl)phenyl)benze...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed