BDBM50321729 2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(3-thienyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile::CHEMBL1170563

SMILES O=C(CSc1nc2CCCCc2c(-c2ccsc2)c1C#N)c1ccccc1

InChI Key InChIKey=DVJXKFMYASKDOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321729   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321729(2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(3-thienyl)-5,...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human recombinant histidine-tagged ALK (103-1459) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321729(2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(3-thienyl)-5,...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of human recombinant histidine-tagged ABL (230-517) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321729(2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(3-thienyl)-5,...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant histidine-tagged RET (700-1020) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed