BDBM50321732 2-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-6-methyl-4-(3-thienyl)-5,6,7,8-tetrahydro[1,6]naphthyridine-3-carbonitrile::CHEMBL1170550

SMILES CN1CCc2nc(SCC(=O)c3ccc(Cl)cc3)c(C#N)c(-c3ccsc3)c2C1

InChI Key InChIKey=TXSFZALDGGIYJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321732   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321732(2-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-6-meth...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human recombinant histidine-tagged RET (700-1020) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed