BDBM50321745 2-(4-fluorobenzylsulfanyl)-4-(2-thienyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile::CHEMBL1172697

SMILES Fc1ccc(CSc2nc3CCCCc3c(-c3cccs3)c2C#N)cc1

InChI Key InChIKey=FJAGVGBQBVTRAB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321745   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321745(2-(4-fluorobenzylsulfanyl)-4-(2-thienyl)-5,6,7,8-t...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant histidine-tagged ALK (103-1459) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321745(2-(4-fluorobenzylsulfanyl)-4-(2-thienyl)-5,6,7,8-t...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of human recombinant histidine-tagged ABL (230-517) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50321745(2-(4-fluorobenzylsulfanyl)-4-(2-thienyl)-5,6,7,8-t...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human recombinant histidine-tagged RET (700-1020) expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed