BDBM50322260 CHEMBL1171289::rac-1-Benzyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride

SMILES CC(C)CC1NC(=O)C2(CCN(Cc3ccc(Oc4ccccc4)cc3)CC2)N(Cc2ccccc2)C1=O

InChI Key InChIKey=ZQTRWSUPLBZZJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322260   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322260(CHEMBL1171289 | rac-1-Benzyl-3-isobutyl-9-(4-pheno...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed