BDBM50322792 3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-4-ol::CHEMBL1173335

SMILES [#6]\[#6](-[#6])=[#6](/c1ccncc1)-c1ccc(cc1)-c1ccc(-[#8])c(F)c1

InChI Key InChIKey=MMMNQMIQOUFMSK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50322792   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322792(3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322792(3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322792(3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of CYP3A4 expressed in baculovirus infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322792(3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)...)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322792(3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed