BDBM50322964 1-(4-chlorophenyl)-N-(3,4-difluorophenyl)-2-isopropyl-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210080

SMILES CC(C)N1CC2(CCN(CC2)C(=O)Nc2ccc(F)c(F)c2)C1c1ccc(Cl)cc1

InChI Key InChIKey=IVIJESHEJVFCAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322964   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322964(1-(4-chlorophenyl)-N-(3,4-difluorophenyl)-2-isopro...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322964(1-(4-chlorophenyl)-N-(3,4-difluorophenyl)-2-isopro...)
Affinity DataIC50:  174nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed