BDBM50323071 4-(4-isopropoxy-3-(trifluoromethyl)phenyl)-6-propylpyrimidine-2-carbonitrile::CHEMBL1209452

SMILES CCCc1cc(nc(n1)C#N)-c1ccc(OC(C)C)c(c1)C(F)(F)F

InChI Key InChIKey=YLWGTLCVWLJFOC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323071   

TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323071(4-(4-isopropoxy-3-(trifluoromethyl)phenyl)-6-propy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323071(4-(4-isopropoxy-3-(trifluoromethyl)phenyl)-6-propy...)
Affinity DataIC50:  91nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323071(4-(4-isopropoxy-3-(trifluoromethyl)phenyl)-6-propy...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323071(4-(4-isopropoxy-3-(trifluoromethyl)phenyl)-6-propy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed