BDBM50323091 2-(4-methoxy-3-(trifluoromethyl)phenyl)-9H-purine-6-carbonitrile::CHEMBL1209530

SMILES COc1ccc(cc1C(F)(F)F)-c1nc(C#N)c2[nH]cnc2n1

InChI Key InChIKey=YTVQPMYKXWVGGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323091   

TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323091(2-(4-methoxy-3-(trifluoromethyl)phenyl)-9H-purine-...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323091(2-(4-methoxy-3-(trifluoromethyl)phenyl)-9H-purine-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed