BDBM50323159 CHEMBL1209321::N-(2-(4-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)piperazin-1-yl)-4-methylpentyl)-N-isopropyl acetamide::N-(2-(4-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)piperazin-1-yl)-4-methylpentyl)-N-isopropylacetamide
SMILES CC(C)CC(CN(C(C)C)C(C)=O)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C
InChI Key InChIKey=NRXOSRAXRKFLQU-CUBVPSHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50323159
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 9.70nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 880nMAssay Description:Agonist activity at human MC3 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 560nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair