BDBM50323159 CHEMBL1209321::N-(2-(4-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)piperazin-1-yl)-4-methylpentyl)-N-isopropyl acetamide::N-(2-(4-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)piperazin-1-yl)-4-methylpentyl)-N-isopropylacetamide

SMILES CC(C)CC(CN(C(C)C)C(C)=O)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C

InChI Key InChIKey=NRXOSRAXRKFLQU-CUBVPSHMSA-N

Data  5 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50323159   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataEC50:  9.70nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataIC50:  4.70E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataEC50:  880nMAssay Description:Agonist activity at human MC3 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataIC50:  23nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323159(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Affinity DataIC50:  3.60E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed