BDBM50323160 CHEMBL1209320::N-(2-(4-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)piperazin-1-yl)-2-cyclohexylethyl)-N,1-di isopropyl-1H-pyrazole-4-carboxamide::N-(2-(4-((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)piperazin-1-yl)-2-cyclohexylethyl)-N,1-diisopropyl-1H-pyrazole-4-carboxamide
SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cnn(c1)C(C)C
InChI Key InChIKey=HLKCUDXXFULFRD-MCYVLLSASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50323160
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Agonist activity at human MC3 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 520nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair