BDBM50323254 1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1208978

SMILES Cc1cccc(CCOc2ccc(cc2C(F)(F)F)-c2cc3n(C)cnc3c(n2)C#N)n1

InChI Key InChIKey=SPMZWMCHCAPLPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323254   

TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323254(1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(...)
Affinity DataIC50:  267nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in human JY cells assessed as accumulation of lip10 by Wes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323254(1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323254(1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(...)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed