BDBM50323366 1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-3-chlorophenylcarbamoyl oxime::CHEMBL1209561

SMILES Fc1cccc(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)c1

InChI Key InChIKey=IDGHBLJDJAIAAN-QVAGMWBUSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323366   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323366(1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323366(1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...)
Affinity DataIC50:  127nMAssay Description:Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed