BDBM50324542 2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone::CHEMBL1214946

SMILES Cn1cc(Cl)c(n1)C(=O)N1CCN(CC(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=QUDDUNFBOHGRTM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324542   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324542(2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to rat 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Canis familiaris)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324542(2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to dog 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324542(2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324542(2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...)
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324542(2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed