BDBM50324583 (R)-N-(2-(2-(Dimethylamino)ethoxy)-3-fluoro-4-(1H-pyrazol-4-yl)phenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1215453

SMILES COc1ccc2CN[C@H](Cc2c1)C(=O)Nc1ccc(-c2cn[nH]c2)c(F)c1OCCN(C)C

InChI Key InChIKey=SCVXFTRWQZQRMC-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324583   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324583((R)-N-(2-(2-(Dimethylamino)ethoxy)-3-fluoro-4-(1H-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324583((R)-N-(2-(2-(Dimethylamino)ethoxy)-3-fluoro-4-(1H-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed