BDBM50324584 (R)-6-Methoxy-N-(2-(2-methoxyethoxy)-4-(1H-pyrazol-4-yl)-phenyl)-1,2,3,4-tetrahydroisoquino-line-3-carboxamide::CHEMBL1215377

SMILES COCCOc1cc(ccc1NC(=O)[C@H]1Cc2cc(OC)ccc2CN1)-c1cn[nH]c1

InChI Key InChIKey=QUSZKYCDXDOFEK-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324584   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324584((R)-6-Methoxy-N-(2-(2-methoxyethoxy)-4-(1H-pyrazol...)
Affinity DataIC50:  339nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324584((R)-6-Methoxy-N-(2-(2-methoxyethoxy)-4-(1H-pyrazol...)
Affinity DataIC50:  25nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed