BDBM50324587 (S)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)-phenyl)-6-chloro-1,2,3,4-tetrahydroiso-quinoline-3-carboxamide::CHEMBL1215170

SMILES CN(C)CCOc1cc(ccc1NC(=O)[C@@H]1Cc2cc(Cl)ccc2CN1)-c1cn[nH]c1

InChI Key InChIKey=DTFXMUGNPMSNRG-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324587   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324587((S)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4...)
Affinity DataIC50:  85nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324587((S)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4...)
Affinity DataIC50:  23nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed