BDBM50324590 (R)-N-(2-(4-(Dimethylamino)-4-oxobutylthio)-4-(3-methyl-1Hpyrazol-4-yl)phenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1215452

SMILES COc1ccc2CN[C@H](Cc2c1)C(=O)Nc1ccc(cc1SCCC(=O)N(C)C)-c1cn[nH]c1

InChI Key InChIKey=SKSMFVZCCJUUTA-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324590   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324590((R)-N-(2-(4-(Dimethylamino)-4-oxobutylthio)-4-(3-m...)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324590((R)-N-(2-(4-(Dimethylamino)-4-oxobutylthio)-4-(3-m...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed