BDBM50324601 (R)-N-(2-(2-(Dimethylamino)ethylthio)-4-(3-methyl-1H-pyrazol-4-yl)phenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1215380

SMILES COc1ccc2CN[C@H](Cc2c1)C(=O)Nc1ccc(cc1SCCN(C)C)-c1cn[nH]c1C

InChI Key InChIKey=XZMUBCUUJRFNJF-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324601   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324601((R)-N-(2-(2-(Dimethylamino)ethylthio)-4-(3-methyl-...)
Affinity DataIC50:  74nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324601((R)-N-(2-(2-(Dimethylamino)ethylthio)-4-(3-methyl-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed