BDBM50324602 (R)-6-Methoxy-N-(2-(1-methylpiperidin-4-yloxy)-4-(1H-pyrazol-4-yl)phenyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxamide::CHEMBL1215306

SMILES COc1ccc2CN[C@H](Cc2c1)C(=O)Nc1ccc(cc1OC1CCN(C)CC1)-c1cn[nH]c1

InChI Key InChIKey=ZIOFZAKRLQFZFM-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324602   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324602((R)-6-Methoxy-N-(2-(1-methylpiperidin-4-yloxy)-4-(...)
Affinity DataIC50:  70nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324602((R)-6-Methoxy-N-(2-(1-methylpiperidin-4-yloxy)-4-(...)
Affinity DataIC50:  3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed