BDBM50325430 CHEMBL1222855::N-((4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)methyl)-6-fluoronicotinamide::N-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}methyl)-6-fluoropyridine-3-carboxamide

SMILES Fc1ccc(cn1)C(=O)NCc1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1

InChI Key InChIKey=FQECDJFBKXFTIW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325430   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50325430(CHEMBL1222855 | N-((4-(5-cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of IGF1R in IGF1R-SAL cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50325430(CHEMBL1222855 | N-((4-(5-cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair