BDBM50325672 5,7,4'-Trihydroxy-3'-methoxyflavanone::CHEMBL490170::HOMOERIODICTYOL

SMILES COc1cc(ccc1O)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1

InChI Key InChIKey=FTODBIPDTXRIGS-ZDUSSCGKSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50325672   

TargetCytochrome P450 1A1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of CYP1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  240nMAssay Description:Inhibition of CYP1B1 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of CYP1A1 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(5,7,4'-Trihydroxy-3'-methoxyflavanone | CHEMBL4901...)
Affinity DataIC50:  240nMAssay Description:Inhibition of CYP1B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed