BDBM50326018 (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyldiphosphoric acid::CHEMBL1242023

SMILES OP(O)(=O)O[C@@H]1[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(=O)OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O

InChI Key InChIKey=UPHPWXPNZIOZJL-XCMZKKERSA-N

Data  1 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50326018   

LigandPNGBDBM50326018((1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonoox...)
Affinity DataKi:  1.90E+4nMAssay Description:Competitive inhibition of Saccharomyces cerevisiae Pho80-Pho85-Pho81-MD catalyzed phosphorylation of Pho4 assessed as increase in substrate concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphate system positive regulatory protein PHO81(Saccharomyces cerevisiae)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50326018((1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonoox...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae Pho81-MD-MD dependent Pho80-Pho85 activity after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50326018((1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonoox...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae Pho80-Pho85-Pho81-MD catalyzed phosphorylation of Pho4-site 6 peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphate system positive regulatory protein PHO81(Saccharomyces cerevisiae)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50326018((1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonoox...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae Pho81-MD-dependent Pho80-Pho85 activity after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphate system positive regulatory protein PHO81(Saccharomyces cerevisiae)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50326018((1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonoox...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae Pho81-MD-MD dependent Pho80-Pho85 activity after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphate system positive regulatory protein PHO81(Saccharomyces cerevisiae)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50326018((1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonoox...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae Pho81-MD-dependent Pho80-Pho85 activity after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed