BDBM50326210 2-(4-Fluorophenylamino)-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)benzamide::CHEMBL1243231

SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(NC(=O)c2ccccc2Nc2ccc(F)cc2)cc1

InChI Key InChIKey=IREKYVHDFKJOHP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326210   

TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326210(2-(4-Fluorophenylamino)-N-(4-(3-(2-(methylamino)py...)
Affinity DataEC50:  28nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed